Anxiety disorders are increasingly prevalent and often respond poorly to standard treatments such as SSRIs or benzodiazepines. Growing evidence suggests ketamine-assisted psychotherapy may offer rapid relief, particularly in treatment-resistant anxiety. By modulating glutamate via NMDA and AMPA receptors, ketamine enhances neuroplasticity and may reduce pathological worry within hours or days. Clinical trials show benefits in social and generalized anxiety, and real-world studies report sustained symptom reduction and decreased suicidal ideation. When combined with psychotherapy and integration, ketamine may help consolidate meaningful and lasting change.